Effectiveness of mechanical cleaning,<br>antibiotics, and induction heating on<br>eradication of Staphylococcus aureus in<br>mature biofilms
Here we used a mature seven- day biofilm model of Staphylococcus aureus, exposed to anti-biotics up to an additional seven days, to establish the effectiveness of either mechanical cleaning or antibiotics or non- contact induction heating, and which combinations could eradicate S. aureus in mature biofilms.
€ 350.000 voor betere behandeling implantaat-infecties door Leidse startup Implant Preservation Devices
€ 𝟑𝟓𝟎.𝟎𝟎𝟎,- 𝐯𝐨𝐨𝐫 𝐛𝐞𝐭𝐞𝐫𝐞 𝐛𝐞𝐡𝐚𝐧𝐝𝐞𝐥𝐢𝐧𝐠 𝐯𝐚𝐧 𝐢𝐦𝐩𝐥𝐚𝐧𝐭𝐚𝐚𝐭-𝐢𝐧𝐟𝐞𝐜𝐭𝐢𝐞𝐬 𝐝𝐨𝐨𝐫 𝐋𝐞𝐢𝐝𝐬𝐞 𝐬𝐭𝐚𝐫𝐭𝐮𝐩 𝐈𝐦𝐩𝐥𝐚𝐧𝐭 𝐏𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧 𝐃𝐞𝐯𝐢𝐜𝐞𝐬 / Bij 1-3% van de gewrichtsvervangende operaties gaat het implantaat infecteren. Dat vormt een enorme belasting voor zowel patiënt als de wereldwijde gezondheidszorg. Huidige behandelingen van die infecties hebben verschillende negatieve implicaties – meerdere operaties, langdurig ziekenhuisverblijf en langdurig gebruik van antibiotica […]
Press release: IPD secures funding of €1.5 million to develop its first-in-human prototype for prosthetic joint infections.
IPD bv (Implant Preservation Devices), a Dutch-based startup specialising in the treatment of prosthetic joint infections, raised €1.5 million of dilutive and non-dilutive financing in 2021, contributing to the development of its first-in-human prototype for a clinical trial set to commence in 2022.Founded in December 2020 by NLC- The European Healthtech Venture Builder and Leiden […]
IPD (Implant Preservation Devices) (https://ipd.health) and IDE group (https://idegroup.com.au) have received a €289K grant from province Zuid-Holland the Netherlands. The submission was prepared together with Prof.Dr. Rob Nelissen and dr. B.Pijls, the inventors from the Leiden University Medical Center in the Netherlands, who collaborate with IPD to bring its exciting orthopedic technology to market.The grant […]
IPD (Implant Preservation Devices) would like to welcome our scientific advisory panel to support us in our journey towards the solution for prosthetic joint and metal implant infections, using antibacterial non-contact induction heating. On a regular base they will advice IPD in the different scientific development phases with their independent expertise, so IPD can develop […]
Recently IPD, #ipdhealth, announced the cooperation with IDE group, #idegroup, as our preferred partner for the development of IPD’s Non-contact induction heating device for the treatment of prosthetic and metal implant infections.Last week Hedon Electronics development, www.hedon.nl, from Delft, the Netherlands, joined our development team. Hedon manufactures since 1990 products for induction heating and is an abslolute expert […]
Staphylococcus aureus is a major cause of prosthetic joint infection (PJI) in which it forms adherent biofilms, thick aggregates of extracellular polymeric substances (EPS) produced by the bacteria. Biofilm associated infections are difficult to treat as they have increased resistance to various antimicrobial agents, which means infected implants often require multiple procedures and prolonged antibiotic therapy. […]
NON-CONTACT INDUCTION HEATING AND SAAP-148 ELIMINATE PERSISTERS WITHIN MRSA BIOFILMS MIMICKING A METAL IMPLANT INFECTION
Implant-associated infections are the primary cause of complications following orthopaedic surgery. Dueto biofilm and persister formation, current treatments, i.e. surgical debridement followed by antibiotics,often fail. There is an urgent need for alternative strategies to combat such infections. Therefore, the presentstudy investigated the effects of non-contact induction heating (NCIH), the antimicrobial peptide SAAP-148and combinations thereof on […]
Recently IPD signed a product development agreement with IDE group in Rotterdam. IDE is an ISO 13485 certified company with locations in Australia, USA and the Netherlands. IDE has a broad experience in medical device product development and will use their expertise to develop IPD’s induction device to treat Prosthetic Joint Infections in the coming […]